Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops

We recently found that hnRNP A1, a protein implicated in many aspects of RNA processing, acts as an auxiliary factor for the Drosha-mediated processing of a microRNA precursor, pri-miR-18a. Here, we provide the mechanism by which hnRNP A1 regulates this event. We show that hnRNP A1 binds to the loop...

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Detalles Bibliográficos
Autores principales: Michlewski, Gracjan, Guil, Sonia, Semple, Colin A., Cáceres, Javier F.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631628/
https://www.ncbi.nlm.nih.gov/pubmed/18995836
http://dx.doi.org/10.1016/j.molcel.2008.10.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631628/
https://www.ncbi.nlm.nih.gov/pubmed/18995836
http://dx.doi.org/10.1016/j.molcel.2008.10.013

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