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Posttranscriptional Regulation of miRNAs Harboring Conserved Terminal Loops
We recently found that hnRNP A1, a protein implicated in many aspects of RNA processing, acts as an auxiliary factor for the Drosha-mediated processing of a microRNA precursor, pri-miR-18a. Here, we provide the mechanism by which hnRNP A1 regulates this event. We show that hnRNP A1 binds to the loop...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631628/ https://www.ncbi.nlm.nih.gov/pubmed/18995836 http://dx.doi.org/10.1016/j.molcel.2008.10.013 |