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Nuclear Factor Y Is Required for Basal Activation and Chromatin Accessibility of Fibroblast Growth Factor Receptor 2 Promoter in Osteoblast-like Cells

Fibroblast growth factor receptor 2 (FGFR2) plays an important regulatory role in bone development. However, the regulatory mechanisms controlling FGFR2 expression remain poorly understood. Here we have identified a role for the nuclear factor Y (NF-Y) in constitutive activation of FGFR2. A unique D...

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Detalles Bibliográficos
Autores principales: Sun, Fenyong, Xie, Qiuling, Ma, Ji, Yang, Songhai, Chen, Qiongyu, Hong, An
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631964/
https://www.ncbi.nlm.nih.gov/pubmed/19047043
http://dx.doi.org/10.1074/jbc.M808992200