The Cytoskeletal Protein α-Actinin Regulates Acid-sensing Ion Channel 1a through a C-terminal Interaction

The acid-sensing ion channel 1a (ASIC1a) is widely expressed in central and peripheral neurons where it generates transient cation currents when extracellular pH falls. ASIC1a confers pH-dependent modulation on postsynaptic dendritic spines and has critical effects in neurological diseases associate...

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Detalles Bibliográficos
Autores principales: Schnizler, Mikael K., Schnizler, Katrin, Zha, Xiang-ming, Hall, Duane D., Wemmie, John A., Hell, Johannes W., Welsh, Michael J.
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2009
Materias:
Membrane Transport, Structure, Function, and Biogenesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631967/
https://www.ncbi.nlm.nih.gov/pubmed/19028690
http://dx.doi.org/10.1074/jbc.M805110200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2631967/
https://www.ncbi.nlm.nih.gov/pubmed/19028690
http://dx.doi.org/10.1074/jbc.M805110200

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