Insulin-degrading enzyme is exported via an unconventional protein secretion pathway

Insulin-degrading enzyme (IDE) is a ubiquitously expressed zinc-metalloprotease that degrades several pathophysiologically significant extracellular substrates, including insulin and the amyloid β-protein (Aβ), and accumulating evidence suggests that IDE dysfunction may be operative in both type 2 d...

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Detalles Bibliográficos
Autores principales: Zhao, Ji, Li, Lilin, Leissring, Malcolm A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632642/
https://www.ncbi.nlm.nih.gov/pubmed/19144176
http://dx.doi.org/10.1186/1750-1326-4-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632642/
https://www.ncbi.nlm.nih.gov/pubmed/19144176
http://dx.doi.org/10.1186/1750-1326-4-4

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