Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability

Overexpression of HER-2/Neu occurs in about 25–30% of breast cancer patients and is indicative of poor prognosis. While Her2/Neu overexpression is primarily a result of erbB2 amplification, it has recently been recognized that erbB2 levels are also regulated on the protein level. However, factors th...

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Detalles Bibliográficos
Autores principales: Lam, Prudence B, Burga, Laura N, Wu, Bryan P, Hofstatter, Erin W, Lu, Kun Ping, Wulf, Gerburg M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632646/
https://www.ncbi.nlm.nih.gov/pubmed/19077306
http://dx.doi.org/10.1186/1476-4598-7-91

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632646/
https://www.ncbi.nlm.nih.gov/pubmed/19077306
http://dx.doi.org/10.1186/1476-4598-7-91

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