Role of the domain encompassing Arg(304)–Ile(328) in rat P2X(2) receptor conformation revealed by alterations in complex glycosylation at Asn(298)

The final 25 amino acids of the ectodomain of the P2X receptors, immediately prior to the second TM (transmembrane domain) (pre-TM2: Arg(304)–Ile(328) in rat P2X(2)), are highly conserved. Whole-cell patch clamp recordings showed that single cysteine substitutions in the N-terminal half of pre-TM2 (...

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Detalles Bibliográficos
Autores principales: Young, Mark T., Zhang, Yi-Hong, Cao, Lishuang, Broomhead, Helen, Jiang, Lin-Hua
Formato: Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632800/
https://www.ncbi.nlm.nih.gov/pubmed/18616429
http://dx.doi.org/10.1042/BJ20081182

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632800/
https://www.ncbi.nlm.nih.gov/pubmed/18616429
http://dx.doi.org/10.1042/BJ20081182

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