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Conformational Changes and Slow Dynamics through Microsecond Polarized Atomistic Molecular Simulation of an Integral Kv1.2 Ion Channel

Structure and dynamics of voltage-gated ion channels, in particular the motion of the S4 helix, is a highly interesting and hotly debated topic in current membrane protein research. It has critical implications for insertion and stabilization of membrane proteins as well as for finding how transitio...

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Detalles Bibliográficos
Autores principales: Bjelkmar, Pär, Niemelä, Perttu S., Vattulainen, Ilpo, Lindahl, Erik
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632863/
https://www.ncbi.nlm.nih.gov/pubmed/19229308
http://dx.doi.org/10.1371/journal.pcbi.1000289