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Ser276 Phosphorylation of NF-kB p65 by MSK1 Controls SCF Expression in Inflammation

Transcription of the mast cell growth factor SCF (stem cell factor) is upregulated in inflammatory conditions, and this is dependent upon NF-κB, as well as the MAP kinases p38 and ERK activation. We show here that the MAPK downstream nuclear kinase MSK1 induces NF-κB p65 Ser276 phosphorylation upon...

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Detalles Bibliográficos
Autores principales: Reber, Laurent, Vermeulen, Linda, Haegeman, Guy, Frossard, Nelly
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632887/
https://www.ncbi.nlm.nih.gov/pubmed/19197368
http://dx.doi.org/10.1371/journal.pone.0004393