Phthiocerol Dimycocerosates of M. tuberculosis Participate in Macrophage Invasion by Inducing Changes in the Organization of Plasma Membrane Lipids

Phthiocerol dimycocerosates (DIM) are major virulence factors of Mycobacterium tuberculosis (Mtb), in particular during the early step of infection when bacilli encounter their host macrophages. However, their cellular and molecular mechanisms of action remain unknown. Using Mtb mutants deleted for...

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Detalles Bibliográficos
Autores principales: Astarie-Dequeker, Catherine, Le Guyader, Laurent, Malaga, Wladimir, Seaphanh, Fam-Ky, Chalut, Christian, Lopez, André, Guilhot, Christophe
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632888/
https://www.ncbi.nlm.nih.gov/pubmed/19197369
http://dx.doi.org/10.1371/journal.ppat.1000289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632888/
https://www.ncbi.nlm.nih.gov/pubmed/19197369
http://dx.doi.org/10.1371/journal.ppat.1000289

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