Structure–function analysis of the ribozymes of chrysanthemum chlorotic mottle viroid: a loop–loop interaction motif conserved in most natural hammerheads

Loop–loop tertiary interactions play a key role in the folding and catalytic activity of natural hammerhead ribozymes. Using a combination of NMR spectroscopy, site-directed mutagenesis and kinetic and infectivity analyses, we have examined the structure and function of loops 1 and 2 of the (+) and...

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Detalles Bibliográficos
Autores principales: Dufour, David, de la Peña, Marcos, Gago, Selma, Flores, Ricardo, Gallego, José
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632901/
https://www.ncbi.nlm.nih.gov/pubmed/19043070
http://dx.doi.org/10.1093/nar/gkn918

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632901/
https://www.ncbi.nlm.nih.gov/pubmed/19043070
http://dx.doi.org/10.1093/nar/gkn918

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