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The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response

The tumor suppressor p53 contributes to the cellular fate after genotoxic insults, mainly through the regulation of target genes, thereby allowing e.g. repair mechanisms resulting in cell survival or inducing apoptosis. Unresolved so far is the issue, which exact mechanisms lead to one or the other...

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Detalles Bibliográficos
Autores principales: Koeppel, Max, van Heeringen, Simon J., Smeenk, Leonie, Navis, Anna C., Janssen-Megens, Eva M., Lohrum, Marion
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632907/
https://www.ncbi.nlm.nih.gov/pubmed/19042971
http://dx.doi.org/10.1093/nar/gkn940