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The novel p53 target gene IRF2BP2 participates in cell survival during the p53 stress response
The tumor suppressor p53 contributes to the cellular fate after genotoxic insults, mainly through the regulation of target genes, thereby allowing e.g. repair mechanisms resulting in cell survival or inducing apoptosis. Unresolved so far is the issue, which exact mechanisms lead to one or the other...
Autores principales: | Koeppel, Max, van Heeringen, Simon J., Smeenk, Leonie, Navis, Anna C., Janssen-Megens, Eva M., Lohrum, Marion |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632907/ https://www.ncbi.nlm.nih.gov/pubmed/19042971 http://dx.doi.org/10.1093/nar/gkn940 |
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