The C-terminal fragment of the ribosomal P protein complexed to trichosanthin reveals the interaction between the ribosome-inactivating protein and the ribosome

Ribosome-inactivating proteins (RIPs) inhibit protein synthesis by enzymatically depurinating a specific adenine residue at the sarcin-ricin loop of the 28S rRNA, which thereby prevents the binding of elongation factors to the GTPase activation centre of the ribosome. Here, we present the 2.2 Å crys...

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Detalles Bibliográficos
Autores principales: Too, Priscilla Hiu-Mei, Ma, Meiji Kit-Wan, Mak, Amanda Nga-Sze, Wong, Yuen-Ting, Tung, Christine Kit-Ching, Zhu, Guang, Au, Shannon Wing-Ngor, Wong, Kam-Bo, Shaw, Pang-Chui
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632931/
https://www.ncbi.nlm.nih.gov/pubmed/19073700
http://dx.doi.org/10.1093/nar/gkn922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632931/
https://www.ncbi.nlm.nih.gov/pubmed/19073700
http://dx.doi.org/10.1093/nar/gkn922

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