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Ctk1 promotes dissociation of basal transcription factors from elongating RNA polymerase II

As RNA polymerase II (RNApII) transitions from initiation to elongation, Mediator and the basal transcription factors TFIID, TFIIA, TFIIH, and TFIIE remain at the promoter as part of a scaffold complex, whereas TFIIB and TFIIF dissociate. The yeast Ctk1 kinase associates with elongation complexes an...

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Detalles Bibliográficos
Autores principales: Ahn, Seong Hoon, Keogh, Michael-Christopher, Buratowski, Stephen
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632940/
https://www.ncbi.nlm.nih.gov/pubmed/19131970
http://dx.doi.org/10.1038/emboj.2008.280