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Conformational changes in α7 acetylcholine receptors underlying allosteric modulation by divalent cations

Allosteric modulation of membrane receptors is a widespread mechanism by which endogenous and exogenous agents regulate receptor function. For example, several members of the nicotinic receptor family are modulated by physiological concentrations of extracellular calcium ions. In this paper, we exam...

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Detalles Bibliográficos
Autores principales: McLaughlin, James T, Barron, Sean C, See, Jennifer A, Rosenberg, Robert L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632993/
https://www.ncbi.nlm.nih.gov/pubmed/19144123
http://dx.doi.org/10.1186/1471-2210-9-1