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Identifying Tumor Cell Growth Inhibitors by Combinatorial Chemistry and Zebrafish Assays
Cyclin-dependent kinases (CDKs) play important roles in regulating cell cycle progression, and altered cell cycles resulting from over-expression or abnormal activation of CDKs observed in many human cancers. As a result, CDKs have become extensive studied targets for developing chemical inhibitors...
Autores principales: | , , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633036/ https://www.ncbi.nlm.nih.gov/pubmed/19194508 http://dx.doi.org/10.1371/journal.pone.0004361 |