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Identifying Tumor Cell Growth Inhibitors by Combinatorial Chemistry and Zebrafish Assays

Cyclin-dependent kinases (CDKs) play important roles in regulating cell cycle progression, and altered cell cycles resulting from over-expression or abnormal activation of CDKs observed in many human cancers. As a result, CDKs have become extensive studied targets for developing chemical inhibitors...

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Detalles Bibliográficos
Autores principales: Xiang, Jing, Yang, Hongbo, Che, Chao, Zou, Haixia, Yang, Hanshuo, Wei, Yuquan, Quan, Junmin, Zhang, Hui, Yang, Zhen, Lin, Shuo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633036/
https://www.ncbi.nlm.nih.gov/pubmed/19194508
http://dx.doi.org/10.1371/journal.pone.0004361