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HECTD2 Is Associated with Susceptibility to Mouse and Human Prion Disease

Prion diseases are fatal transmissible neurodegenerative disorders, which include Scrapie, Bovine Spongiform Encephalopathy (BSE), Creutzfeldt-Jakob Disease (CJD), and kuru. They are characterised by a prolonged clinically silent incubation period, variation in which is determined by many factors, i...

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Detalles Bibliográficos
Autores principales: Lloyd, Sarah E., Maytham, Emma G., Pota, Hirva, Grizenkova, Julia, Molou, Eleni, Uphill, James, Hummerich, Holger, Whitfield, Jerome, Alpers, Michael P., Mead, Simon, Collinge, John
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633041/
https://www.ncbi.nlm.nih.gov/pubmed/19214206
http://dx.doi.org/10.1371/journal.pgen.1000383