Production of recombinant AAV vectors encoding insulin-like growth factor I is enhanced by interaction among AAV rep regulatory sequences

BACKGROUND: Adeno-associated virus (AAV) vectors are promising tools for gene therapy. Currently, their potential is limited by difficulties in producing high vector yields with which to generate transgene protein product. AAV vector production depends in part upon the replication (Rep) proteins req...

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Detalles Bibliográficos
Autores principales: Shi, Shuiliang, Mercer, Scott A, Dilley, Robert, Trippel, Stephen B
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633264/
https://www.ncbi.nlm.nih.gov/pubmed/19128486
http://dx.doi.org/10.1186/1743-422X-6-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633264/
https://www.ncbi.nlm.nih.gov/pubmed/19128486
http://dx.doi.org/10.1186/1743-422X-6-3

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