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Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella

BACKGROUND: There is no safe, effective human vaccine against brucellosis. Live attenuated Brucella strains are widely used to vaccinate animals. However these live Brucella vaccines can cause disease and are unsafe for humans. Killed Brucella or subunit vaccines are not effective in eliciting long...

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Detalles Bibliográficos
Autores principales: Harms, Jerome S, Durward, Marina A, Magnani, Diogo M, Splitter, Gary A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633335/
https://www.ncbi.nlm.nih.gov/pubmed/19126207
http://dx.doi.org/10.1186/1476-8518-7-1