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Evaluation of recombinant invasive, non-pathogenic Eschericia coli as a vaccine vector against the intracellular pathogen, Brucella
BACKGROUND: There is no safe, effective human vaccine against brucellosis. Live attenuated Brucella strains are widely used to vaccinate animals. However these live Brucella vaccines can cause disease and are unsafe for humans. Killed Brucella or subunit vaccines are not effective in eliciting long...
Autores principales: | Harms, Jerome S, Durward, Marina A, Magnani, Diogo M, Splitter, Gary A |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633335/ https://www.ncbi.nlm.nih.gov/pubmed/19126207 http://dx.doi.org/10.1186/1476-8518-7-1 |
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