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Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism

BACKGROUND: Elevated plasma cholesterol promotes the formation of atherosclerotic lesions in which monocyte-derived lipid-laden macrophages are frequently found. To analyze, if circulating monocytes already show increased lipid content and differences in lipoprotein metabolism, we compared monocytes...

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Detalles Bibliográficos
Autores principales: Mosig, Sandy, Rennert, Knut, Büttner, Petra, Krause, Siegfried, Lütjohann, Dieter, Soufi, Muhidien, Heller, Regine, Funke, Harald
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633353/
https://www.ncbi.nlm.nih.gov/pubmed/19040724
http://dx.doi.org/10.1186/1755-8794-1-60