Gene therapy following subretinal AAV5 vector delivery is not affected by a previous intravitreal AAV5 vector administration in the partner eye

PURPOSE: In an earlier study we found normal adeno-associated viral vector type 2 (AAV2)-mediated GFP expression after intravitreal injection to one eye of normal C57BL/6J mice. However, GFP expression was very poor in the partner eye of the same mouse if this eye received an intravitreal injection...

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Detalles Bibliográficos
Autores principales: Li, Wensheng, Kong, Fansheng, Li, Xia, Dai, Xufeng, Liu, Xiaoqiang, Zheng, Qinxiang, Wu, Ronghan, Zhou, Xiangtian, Lü, Fan, Chang, Bo, Li, Qiuhong, Hauswirth, William W., Qu, Jia, Pang, Ji-jing
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633462/
https://www.ncbi.nlm.nih.gov/pubmed/19190735

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633462/
https://www.ncbi.nlm.nih.gov/pubmed/19190735

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