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Defects in retinal pigment epithelium cell proliferation and retinal attachment in mutant mice with p27(Kip1) gene ablation

PURPOSE: Little is known about the mechanisms that regulate cell cycle withdrawal of the retinal pigment epithelium (RPE) during development, or about the mechanisms maintaining epithelial cell quiescence in adult retinas. The present study examines the potential role of the negative cell cycle regu...

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Detalles Bibliográficos
Autores principales: Defoe, Dennis M., Adams, Lorrie B. S., Sun, Jingru, Wisecarver, Sarah N., Levine, Edward M.
Formato: Texto
Lenguaje:English
Publicado: Molecular Vision 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633469/
https://www.ncbi.nlm.nih.gov/pubmed/17356514