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Plasma Neutrophil Elastase and Elafin Imbalance Is Associated with Acute Respiratory Distress Syndrome (ARDS) Development

BACKGROUND: We conducted an exploratory study of genome-wide gene expression in whole blood and found that the expression of neutrophil elastase inhibitor (PI3, elafin) was down-regulated during the early phase of ARDS. Further analyses of plasma PI3 levels revealed a rapid decrease during early ARD...

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Detalles Bibliográficos
Autores principales: Wang, Zhaoxi, Chen, Feng, Zhai, Rihong, Zhang, Lingsong, Su, Li, Lin, Xihong, Thompson, Taylor, Christiani, David C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633615/
https://www.ncbi.nlm.nih.gov/pubmed/19197381
http://dx.doi.org/10.1371/journal.pone.0004380