Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration

Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocytosis and retinal degeneration. In these mutants, r...

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Detalles Bibliográficos
Autores principales: Chinchore, Yashodhan, Mitra, Amitavo, Dolph, Patrick J.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633617/
https://www.ncbi.nlm.nih.gov/pubmed/19214218
http://dx.doi.org/10.1371/journal.pgen.1000377

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633617/
https://www.ncbi.nlm.nih.gov/pubmed/19214218
http://dx.doi.org/10.1371/journal.pgen.1000377

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