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Accumulation of Rhodopsin in Late Endosomes Triggers Photoreceptor Cell Degeneration
Progressive retinal degeneration is the underlying feature of many human retinal dystrophies. Previous work using Drosophila as a model system and analysis of specific mutations in human rhodopsin have uncovered a connection between rhodopsin endocytosis and retinal degeneration. In these mutants, r...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2633617/ https://www.ncbi.nlm.nih.gov/pubmed/19214218 http://dx.doi.org/10.1371/journal.pgen.1000377 |