Cross talk of signals between EGFR and IL-6R through JAK2/STAT3 mediate epithelial–mesenchymal transition in ovarian carcinomas

Epidermal growth factor receptor (EGFR) is overexpressed in ovarian carcinomas, with direct or indirect activation of EGFR able to trigger tumour growth. We demonstrate significant activation of both signal transducer and activator of transcription (STAT)3 and its upstream activator Janus kinase (JA...

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Detalles Bibliográficos
Autores principales: Colomiere, M, Ward, A C, Riley, C, Trenerry, M K, Cameron-Smith, D, Findlay, J, Ackland, L, Ahmed, N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634691/
https://www.ncbi.nlm.nih.gov/pubmed/19088723
http://dx.doi.org/10.1038/sj.bjc.6604794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634691/
https://www.ncbi.nlm.nih.gov/pubmed/19088723
http://dx.doi.org/10.1038/sj.bjc.6604794

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