LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model

Persistent activation of the signal transducer and activator of transcription 3 (STAT3) signalling has been linked to oncogenesis and the development of chemotherapy resistance in glioblastoma and other cancers. Inhibition of the STAT3 pathway thus represents an attractive therapeutic approach for c...

Descripción completa

Detalles Bibliográficos
Autores principales: Fuh, B, Sobo, M, Cen, L, Josiah, D, Hutzen, B, Cisek, K, Bhasin, D, Regan, N, Lin, L, Chan, C, Caldas, H, DeAngelis, S, Li, C, Li, P-K, Lin, J
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634692/
https://www.ncbi.nlm.nih.gov/pubmed/19127268
http://dx.doi.org/10.1038/sj.bjc.6604793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634692/
https://www.ncbi.nlm.nih.gov/pubmed/19127268
http://dx.doi.org/10.1038/sj.bjc.6604793

Ejemplares similares