Promoter CpG methylation in cancer cells contributes to the regulation of MUC4

Mucin 4 (MUC4) is a high molecular weight transmembrane mucin that is overexpressed in many carcinomas and is a risk factor associated with a poor prognosis. In this study, we show that the DNA methylation pattern is intimately correlated with MUC4 expression in breast, lung, pancreas and colon canc...

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Detalles Bibliográficos
Autores principales: Yamada, N, Nishida, Y, Tsutsumida, H, Goto, M, Higashi, M, Nomoto, M, Yonezawa, S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634723/
https://www.ncbi.nlm.nih.gov/pubmed/19127263
http://dx.doi.org/10.1038/sj.bjc.6604845

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634723/
https://www.ncbi.nlm.nih.gov/pubmed/19127263
http://dx.doi.org/10.1038/sj.bjc.6604845

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