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A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer

Brain metastases represent an important cause of morbidity in patients with lung cancer and are associated with a mean survival of less than 6 months. Thus, new regimens improving the outcome of these patients are urgently needed. On the basis of promising data raised in a phase I/II trial, we initi...

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Detalles Bibliográficos
Autores principales: Neuhaus, T, Ko, Y, Muller, R P, Grabenbauer, G G, Hedde, J P, Schueller, H, Kocher, M, Stier, S, Fietkau, R
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634726/
https://www.ncbi.nlm.nih.gov/pubmed/19127261
http://dx.doi.org/10.1038/sj.bjc.6604835