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A phase III trial of topotecan and whole brain radiation therapy for patients with CNS-metastases due to lung cancer
Brain metastases represent an important cause of morbidity in patients with lung cancer and are associated with a mean survival of less than 6 months. Thus, new regimens improving the outcome of these patients are urgently needed. On the basis of promising data raised in a phase I/II trial, we initi...
Autores principales: | Neuhaus, T, Ko, Y, Muller, R P, Grabenbauer, G G, Hedde, J P, Schueller, H, Kocher, M, Stier, S, Fietkau, R |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634726/ https://www.ncbi.nlm.nih.gov/pubmed/19127261 http://dx.doi.org/10.1038/sj.bjc.6604835 |
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