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A randomised pilot Phase II study of doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC) given 2 weekly with pegfilgrastim (accelerated) vs 3 weekly (standard) for women with early breast cancer

Accelerated (dose-dense) chemotherapy, in which the frequency of administration is increased without changing total dose or duration, may increase the efficacy of cancer chemotherapy. We performed a randomised Phase II study to assess the safety and relative toxicity of AC (doxorubicin; cyclophospha...

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Detalles Bibliográficos
Autores principales: Jones, R L, Walsh, G, Ashley, S, Chua, S, Agarwal, R, O'Brien, M, Johnston, S, Smith, I E
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634727/
https://www.ncbi.nlm.nih.gov/pubmed/19165198
http://dx.doi.org/10.1038/sj.bjc.6604862