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Minor contribution of mutations at iniA codon 501 and embC-embA intergenic region in ethambutol-resistant clinical Mycobacterium tuberculosis isolates in Kuwait

BACKGROUND: Ethambutol (EMB) is a first-line drug for the treatment of tuberculosis (TB). Resistance to EMB in Mycobacterium tuberculosis isolates is mediated by mutations in several genes involved in arabinan synthesis notably three emb (arabinosyl transferase) and iniA (isoniazid-inducible) genes....

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Detalles Bibliográficos
Autores principales: Jaber, Al-Anoud, Ahmad, Suhail, Mokaddas, Eiman
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634755/
https://www.ncbi.nlm.nih.gov/pubmed/19146672
http://dx.doi.org/10.1186/1476-0711-8-2