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Cryptic Variation in the Human Mutation Rate
The mutation rate is known to vary between adjacent sites within the human genome as a consequence of context, the most well-studied example being the influence of CpG dinucelotides. We investigated whether there is additional variation by testing whether there is an excess of sites at which both hu...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634788/ https://www.ncbi.nlm.nih.gov/pubmed/19192947 http://dx.doi.org/10.1371/journal.pbio.1000027 |