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Cryptic Variation in the Human Mutation Rate

The mutation rate is known to vary between adjacent sites within the human genome as a consequence of context, the most well-studied example being the influence of CpG dinucelotides. We investigated whether there is additional variation by testing whether there is an excess of sites at which both hu...

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Detalles Bibliográficos
Autores principales: Hodgkinson, Alan, Ladoukakis, Emmanuel, Eyre-Walker, Adam
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634788/
https://www.ncbi.nlm.nih.gov/pubmed/19192947
http://dx.doi.org/10.1371/journal.pbio.1000027