Activation of DNA-PK by Ionizing Radiation Is Mediated by Protein Phosphatase 6

DNA-dependent protein kinase (DNA-PK) plays a critical role in DNA damage repair, especially in non-homologous end-joining repair of double-strand breaks such as those formed by ionizing radiation (IR) in the course of radiation therapy. Regulation of DNA-PK involves multisite phosphorylation but th...

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Detalles Bibliográficos
Autores principales: Mi, Jun, Dziegielewski, Jaroslaw, Bolesta, Elzbieta, Brautigan, David L., Larner, James M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634843/
https://www.ncbi.nlm.nih.gov/pubmed/19198648
http://dx.doi.org/10.1371/journal.pone.0004395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634843/
https://www.ncbi.nlm.nih.gov/pubmed/19198648
http://dx.doi.org/10.1371/journal.pone.0004395

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