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Activation of DNA-PK by Ionizing Radiation Is Mediated by Protein Phosphatase 6
DNA-dependent protein kinase (DNA-PK) plays a critical role in DNA damage repair, especially in non-homologous end-joining repair of double-strand breaks such as those formed by ionizing radiation (IR) in the course of radiation therapy. Regulation of DNA-PK involves multisite phosphorylation but th...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634843/ https://www.ncbi.nlm.nih.gov/pubmed/19198648 http://dx.doi.org/10.1371/journal.pone.0004395 |