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HDAC3 as a Molecular Chaperone for Shuttling Phosphorylated TR2 to PML: A Novel Deacetylase Activity-Independent Function of HDAC3

TR2 is an orphan nuclear receptor specifically expressed in early embryos (Wei and Hsu, 1994), and a transcription factor for transcriptional regulation of important genes in stem cells including the gate keeper Oct4 (Park et al. 2007). TR2 is known to function as an activator (Wei et al. 2000), or...

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Detalles Bibliográficos
Autores principales: Gupta, Pawan, Ho, Ping-Chih, Ha, Sung Gil, Lin, Yi-Wei, Wei, Li-Na
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634961/
https://www.ncbi.nlm.nih.gov/pubmed/19204783
http://dx.doi.org/10.1371/journal.pone.0004363