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Allosteric Communication Occurs via Networks of Tertiary and Quaternary Motions in Proteins
Allosteric proteins bind an effector molecule at one site resulting in a functional change at a second site. We hypothesize that allosteric communication in proteins relies upon networks of quaternary (collective, rigid-body) and tertiary (residue–residue contact) motions. We argue that cyclic topol...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2634971/ https://www.ncbi.nlm.nih.gov/pubmed/19229311 http://dx.doi.org/10.1371/journal.pcbi.1000293 |