PD-1 Regulates Neural Damage in Oligodendroglia-Induced Inflammation

We investigated the impact of immune regulatory mechanisms involved in the modulation of the recently presented, CD8+ lymphocyte mediated immune response in a mouse model of oligodendropathy-induced inflammation (PLPtg-mutants). The focus was on the role of the co-inhibitory molecule PD-1, a CD28-re...

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Detalles Bibliográficos
Autores principales: Kroner, Antje, Schwab, Nicholas, Ip, Chi Wang, Leder, Christoph, Nave, Klaus-Armin, Mäurer, Mathias, Wiendl, Heinz, Martini, Rudolf
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635015/
https://www.ncbi.nlm.nih.gov/pubmed/19197390
http://dx.doi.org/10.1371/journal.pone.0004405

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635015/
https://www.ncbi.nlm.nih.gov/pubmed/19197390
http://dx.doi.org/10.1371/journal.pone.0004405

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