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The function of APC/C(Cdh1 )in cell cycle and beyond

The anaphase promoting complex/cyclosome (APC/C) is a multi-subunit E3 ubiquitin ligase playing essential functions in mitosis. It is conserved from yeast to human and relies on two adaptor proteins, Cdc20 and Cdh1, to bring in substrates. Both APC(Cdc20 )and APC(Cdh1 )are implicated in the control...

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Detalles Bibliográficos
Autores principales: Li, Min, Zhang, Pumin
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635356/
https://www.ncbi.nlm.nih.gov/pubmed/19152694
http://dx.doi.org/10.1186/1747-1028-4-2