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Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression

BACKGROUND: Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown. Adenoid cystic carcinoma is well known as a malignant salivary gland tumor which p...

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Detalles Bibliográficos
Autores principales: Fukuda, Masakatsu, Kusama, Kaoru, Sakashita, Hideaki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635382/
https://www.ncbi.nlm.nih.gov/pubmed/19091137
http://dx.doi.org/10.1186/1471-2407-8-376