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Cimetidine inhibits salivary gland tumor cell adhesion to neural cells and induces apoptosis by blocking NCAM expression
BACKGROUND: Cimetidine, a histamine type-2 receptor antagonist, has been reported to inhibit the growth of glandular tumors such as colorectal cancer, however the mechanism of action underlying this effect is unknown. Adenoid cystic carcinoma is well known as a malignant salivary gland tumor which p...
Autores principales: | Fukuda, Masakatsu, Kusama, Kaoru, Sakashita, Hideaki |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635382/ https://www.ncbi.nlm.nih.gov/pubmed/19091137 http://dx.doi.org/10.1186/1471-2407-8-376 |
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