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Detecting microRNA binding and siRNA off-target effects from expression data

Sylamer is a method for detecting microRNA target and small interfering (si)RNA off-target signals from expression data. The input is a ranked genelist from up to downregulated 3′ untranslated regions (UTRs) following an miRNA or RNAi experiment. The output is a landscape plot that tracks occurrence...

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Detalles Bibliográficos
Autores principales: van Dongen, Stijn, Abreu-Goodger, Cei, Enright, Anton J
Formato: Texto
Lenguaje:English
Publicado: 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635553/
https://www.ncbi.nlm.nih.gov/pubmed/18978784
http://dx.doi.org/10.1038/nmeth.1267