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Detecting microRNA binding and siRNA off-target effects from expression data
Sylamer is a method for detecting microRNA target and small interfering (si)RNA off-target signals from expression data. The input is a ranked genelist from up to downregulated 3′ untranslated regions (UTRs) following an miRNA or RNAi experiment. The output is a landscape plot that tracks occurrence...
Autores principales: | van Dongen, Stijn, Abreu-Goodger, Cei, Enright, Anton J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635553/ https://www.ncbi.nlm.nih.gov/pubmed/18978784 http://dx.doi.org/10.1038/nmeth.1267 |
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