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Detection of FLT3 Oncogene Mutations in Acute Myeloid Leukemia Using Conformation Sensitive Gel Electrophoresis

FLT3 (fms-related tyrosine kinase 3) is a receptor tyrosine kinase class III that is expressed on by early hematopoietic progenitor cells and plays an important role in hematopoietic stem cell proliferation, differentiation and survival. FLT3 is also expressed on leukemia blasts in most cases of acu...

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Detalles Bibliográficos
Autores principales: Gari, Mamdooh, Abuzenadah, Adel, Chaudhary, Adeel, Al-Qahtani, Mohammed, Banni, Huda, Ahmad, Waseem, Al-Sayes, Fatin, Lary, Sahira, Damanhouri, Ghazi
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635624/
https://www.ncbi.nlm.nih.gov/pubmed/19330068
http://dx.doi.org/10.3390/ijms9112194