Pravastatin Prevents Aortic Atherosclerosis via Modulation of Signal Transduction and Activation of Transcription 3 (STAT3) to Attenuate Interleukin-6 (IL-6) Action in ApoE Knockout Mice

The purpose of this study was to determine whether pravastatin’s prevention of aortic atherosclerosis via attenuation of IL-6 action depends on modulation of STAT3 activity. Male apoE knockout (apoE-/-) mice fed on a diet containing 1.25% cholesterol (wt/wt) were divided into pravastatin group provi...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaoxu, Li, Dan, Yan, Wei, Li, Weimin
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635628/
https://www.ncbi.nlm.nih.gov/pubmed/19330073
http://dx.doi.org/10.3390/ijms9112253

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635628/
https://www.ncbi.nlm.nih.gov/pubmed/19330073
http://dx.doi.org/10.3390/ijms9112253

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