RNA Interference in Mammalia Cells by RNA-3’-PNA Chimeras

The discovery of siRNAs as the mediators of RNA interference has led to an increasing interest in their therapeutic applications. Chemical modifications are introduced into siRNAs to optimize the potency, the stability and the pharmacokinetic properties in vivo. Here, we synthesize and test the effe...

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Detalles Bibliográficos
Autores principales: Potenza, Nicoletta, Moggio, Loredana, Milano, Giovanna, Salvatore, Vincenzo, Di Blasio, Benedetto, Russo, Aniello, Messere, Anna
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635679/
https://www.ncbi.nlm.nih.gov/pubmed/19325750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635679/
https://www.ncbi.nlm.nih.gov/pubmed/19325750

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