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Sublethal RNA Oxidation as a Mechanism for Neurodegenerative Disease

Although cellular RNA is subjected to the same oxidative insults as DNA and other cellular macromolecules, oxidative damage to RNA has not been a major focus in investigations of the biological consequences of free radical damage. In fact, because it is largely single-stranded and its bases lack the...

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Detalles Bibliográficos
Autores principales: Castellani, Rudy J., Nunomura, Akihiko, Rolston, Raj K., Moreira, Paula I., Takeda, Atsushi, Perry, George, Smith, Mark A.
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635712/
https://www.ncbi.nlm.nih.gov/pubmed/19325784
http://dx.doi.org/10.3390/ijms9050789