QSAR Study of p56(lck) Protein Tyrosine Kinase Inhibitory Activity of Flavonoid Derivatives Using MLR and GA-PLS

Quantitative relationships between molecular structure and p56(lck) protein tyrosine kinase inhibitory activity of 50 flavonoid derivatives are discovered by MLR and GA-PLS methods. Different QSAR models revealed that substituent electronic descriptors (SED) parameters have significant impact on pro...

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Detalles Bibliográficos
Autores principales: Fassihi, Afshin, Sabet, Razieh
Formato: Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2008
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635749/
https://www.ncbi.nlm.nih.gov/pubmed/19325836
http://dx.doi.org/10.3390/ijms9091876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2635749/
https://www.ncbi.nlm.nih.gov/pubmed/19325836
http://dx.doi.org/10.3390/ijms9091876

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